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Zolpidem (Zolpidem Tartrate)

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Zolpidem is a type of prescription sleeping pill used for short-term treatment of insomnia and other sleep disorders. It has a calming effect, helping people fall asleep more easily and stay asleep through the night. This can lead to better quality sleep and feeling more rested. Zolpidem is a generic medication, also known by the brand name Ambien.

  • Helps you to fall and stay asleep
  • Part of the sedative-hypnotic group of medicines
  • Reduces the number of times you wake up in the night
  • 100% genuine medication
  • Shipped from registered pharmacies
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More Information

A Pharmacist's Overview

Amardeep Bagga (MPharm, MBA) - GPhC Number 2226023

Pharmacist, Amardeep Bagga (MPharm, MBA) provides a simple explanation of the medication below:

'Zolpidem is a short-term treatment for insomnia that promotes faster sleep onset and improves sleep duration.'.

If you think this is a treatment that can help you, start an online consultation now for a registered prescriber to review. If treatment is deemed suitable, they can prescribe it, and we can deliver it to you from the comfort of your own home with a range of convenient delivery and payment options for you to choose from. If you have any questions about a medication, you should always consult your doctor with any questions prior to starting treatment, to ensure that it is safe and suitable for you.

Buy Zolpidem

A prescriber must assess whether zolpidem is suitable for you before prescribing it.

You can buy zolpidem online at PharmXtra after completing our online consultation. If approved, a registered doctor will issue a prescription.

Type of drugNonbenzodiazepine (Z drugs) / Central Nervous System (CNS) depressants / Sleeping pill
Health conditions prescribed forInsomnia (including primary insomnia and chronic insomnia)
Active IngredientsZolpidem tartrate
Available strengths10mg
Available asTablets, modified release tablets (Zolpidem MR / Ambien CR)
Possible side effectsBitter/metallic taste in the mouth, dry mouth, feeling sleepy/tired the next day, headaches, feeling dizzy, nausea, vomiting, diarrhoea, back pain

Zolpidem - Key Information

  • Zolpidem is a type of sleeping tablet.
  • It is prescribed to help with short-term insomnia.
  • It is usually not prescribed for more than four weeks.
  • Zolpidem takes around one hour to work.
  • It belongs to a group of prescription drugs known as Nonbenzodiazepine (Z drugs)/CNS depressants.
  • Zolpidem has no anticonvulsant or muscle relaxant properties
  • You should avoid alcohol while taking zolpidem, as it can make it harder to wake up the next morning.
  • Zolpidem is also known by brand names such as Stilnoct, Ambien, and Ambien CR.
  • It is important to read the patient leaflet for a complete list of side effects and cautions.

Take a look at the video below to get a simple overview of Zolpidem, including what it is used for, dosages, side effects and precautions:

Zolpidem is a prescription medicine that increases levels of GABA (gamma-aminobutyric acid) in the brain. This blocks certain brain chemicals, helping to calm the central nervous system, which promotes relaxation and sleep.

The body can become used to zolpidem, leading to dependence if taken for too long. Stopping it suddenly may cause withdrawal symptoms. This is why doctors usually prescribe it for short periods to help with temporary sleep difficulties. When taken as prescribed, the risk of dependence is low.

Zolpidem Tablets

Zolpidem should be taken at night, just before going to bed.

It causes drowsiness, so only take it when you are ready to sleep.

The tablets should be swallowed with water and can be taken with or without food.

Each person’s experience with zolpidem varies.

User Reviews for Zolpidem

You can read user reviews on Drugs.com and Web MD.

For more details, please refer to the Zolpidem (Zolpidem tartrate) patient information leaflet.

Dosage

Zolpidem 5mg / 10mg

Zolpidem comes in 5mg and 10mg tablets. The usual dose is 10mg at bedtime.

A 5mg dose may be recommended for people over 65 or those with kidney or liver disease, as they may be more sensitive to its effects.

Some people may be advised to take zolpidem only when needed, rather than every night.

It is important to follow your doctor's instructions carefully.

Side Effects

Like all medications, zolpidem use can have some side effects. The most common side effects include:

  • A bitter or metallic taste in the mouth
  • Dry mouth
  • Withdrawal symptoms
  • Breathing difficulties
  • Feeling drowsy the next day – avoid driving or operating machinery if this happens
  • Risk of dependence
  • Liver problems

These effects usually settle over time, but if they are troublesome, speak to a doctor or pharmacist.

Occasionally, more serious side effects can occur when taking zolpidem. These include:

  • Memory loss (amnesia)
  • Increased risk of falls, especially in older adults
  • Hallucinations (seeing things that aren’t real)
  • Delusions (believing things that aren’t true)
  • Feeling depressed or low

If you experience any of these, seek medical advice immediately.

If you have difficulty breathing or swelling of the lips or tongue, call 999 immediately.

Warnings

Zolpidem may not be suitable for everyone. You should tell your doctor if you:

  • Have had an allergic reaction to medication before
  • Have liver or kidney disease
  • Have myasthenia gravis
  • Have breathing difficulties or sleep apnoea
  • Have a history of mental health conditions
  • Have had alcohol or drug dependency
  • Are pregnant, trying to conceive, or breastfeeding

Some medications can interact with zolpidem or make its sedative effect greater. You may be advised that zolpidem will not suit you (due to drug interactions) if you already take:

  • Other sleeping tablets
  • Strong painkillers (codeine, tramadol, methadone, oxycodone)
  • Drowsy antihistamines (chlorphenamine, promethazine)
  • Medications for schizophrenia or bipolar disorder
  • Antidepressants
  • Anxiety medications
  • Antifungal medications (itraconazole, ketoconazole)
  • Ritonavir (used to treat HIV)

Always inform your doctor about any medications, supplements, or herbal remedies you take.

Zolpidem is a sleeping aid, similar to diazepam, which is also used for anxiety. If anxiety is causing your sleep problems, you may want to ask your doctor about Zopiclone are different medications. Both are used to treat sleep problems, but they work differently. Zopiclone is sold under the brand name  Zimovane. Zolpidem can be purchased under the brand name of Ambien.

Medical Reviewer

Medical Reviewer

Irfan Siddique

Deputy Medical Superintendent (DMS) • MBBS

Dr Irfan Siddique is a qualified Medical Doctor licensed to practise in the UK by the General Medical Council (GMC). He earned his MBBS degree in 2017 from the University of Health Sciences, Lahore, and brings years of clinical experience and medical knowledge to his work.

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