Zopiclone and Pregnancy: Can You Take Zopiclone When You Are Pregnant?

Many people experience sleep difficulties during pregnancy, and some may already be taking medication for insomnia before becoming pregnant. Zopiclone is a commonly prescribed sleeping tablet, but its safety in pregnancy is not always clear. In this article, we explain what zopiclone is, the potential risks during pregnancy and the alternatives available. We will also cover what to do if you are already taking zopiclone and find out you are pregnant.

Key Takeaways

Here are the five biggest takeaways from this article regarding the use of zopiclone during pregnancy:

Zopiclone is a prescription-only medicine used for short-term treatment of insomnia.
Zopiclone is not usually recommended during pregnancy because of potential risks to both the mother and baby.
Using zopiclone in the first trimester has not been linked to major birth defects, but evidence is limited.
Taking zopiclone later in pregnancy may cause drowsiness or breathing problems in newborn babies.
Safer alternatives, including sleep hygiene and non-medical therapies, are recommended and should be discussed with a healthcare professional.

What is Zopiclone?

Zopiclone is a type of sleeping pill known as a hypnotic or sedative. It is commonly prescribed to treat insomnia, particularly when problems are severe, disabling, or causing distress. Zopiclone works by affecting the brain’s chemical balance, helping people fall asleep faster and stay asleep longer. It is usually recommended for short-term use only, as long-term use can lead to dependence and tolerance.

Zopiclone and Pregnancy: What do we know?

Research on the safety of zopiclone during pregnancy is limited. According to the NHS, zopiclone is not usually recommended in pregnancy because it may affect the baby, particularly if taken regularly or later in pregnancy [1].

Babies exposed to zopiclone may experience withdrawal symptoms or breathing problems for a few days after birth. For this reason, doctors will often advise against its use during pregnancy unless the benefits clearly outweigh the risks.

Is Zopiclone safe during pregnancy?

First-trimester risks

Studies looking at over 1,500 pregnancies where zopiclone was used in the first trimester have not shown a significant increase in the risk of major birth defects [2]. However, evidence is limited and further research is needed. Healthcare providers may still recommend avoiding zopiclone early in pregnancy, unless there are no safer options.

Later pregnancy risks

Taking zopiclone in the later stages of pregnancy may cause problems for the baby after birth. Newborns may be more likely to experience drowsiness, low muscle tone, or breathing difficulties [3]. Because of these risks, zopiclone is generally avoided in the second and third trimesters unless medically necessary.

Newborn effects

Some babies exposed to zopiclone before birth may show withdrawal symptoms such as irritability, feeding difficulties, or unusual sleepiness. These effects usually improve within a few days and do not require long-term treatment [4]. However, monitoring in the early days after birth is often recommended.

Taking Zopiclone in the First Trimester of Pregnancy

A common question is: “Can you take zopiclone in early pregnancy?” or “Is zopiclone safe in the first trimester?”

Zopiclone is generally not recommended in pregnancy because little is known about its effects. If you discover you are pregnant while taking zopiclone, you should not stop suddenly without speaking to your doctor. They can help you decide on the best course of action and may suggest switching to a safer alternative.

In some cases, if your insomnia is severe and affecting your well-being, your doctor may weigh up the benefits and risks before advising whether to continue or stop.

Has anyone taken Zopiclone during pregnancy?

Some people have taken zopiclone during pregnancy, usually when the benefits were thought to outweigh the risks. Experiences vary, with some women reporting no problems, while others highlight concerns about withdrawal symptoms in newborns or longer-term effects.

Since research is still limited, it is important to have an open discussion with your GP or midwife if you are considering or already taking zopiclone in pregnancy. They can provide personalised advice and explore safer treatment options.

Alternatives to Zopiclone in Pregnancy

If you are struggling with insomnia during pregnancy, there are safer approaches to try before considering medication. These include:

Practising good sleep hygiene, such as keeping a consistent bedtime routine and avoiding caffeine late in the day
Practising relaxation techniques, including breathing exercises, meditation, or gentle yoga
Trying talking therapies such as cognitive behavioural therapy (CBT) for insomnia

In some cases, your doctor may suggest short-term use of alternative medicines that are considered safer in pregnancy.

What To Do If You Are Pregnant and Taking Zopiclone

Do not stop suddenly without advice: Suddenly stopping zopiclone can lead to withdrawal symptoms and worsening insomnia.
Speak to your GP or midwife: They can guide you on the safest way forward and discuss alternatives.
Be honest about your use: Always let your healthcare team know what medicines you are taking, including over-the-counter and herbal treatments, so that they can give you the best possible care.

Final Thoughts

Zopiclone is a medicine often used to treat insomnia, but it is not usually recommended during pregnancy due to potential risks for the baby, particularly later in pregnancy. While first-trimester use has not been strongly linked to birth defects, more research is needed to confirm safety. Safer alternatives, including lifestyle changes and non-drug therapies, should always be considered first. If you are already taking zopiclone and find out you are pregnant, get medical advice before making any changes to your treatment.